                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    {"id":4708,"date":"2020-03-14T11:36:32","date_gmt":"2020-03-14T11:36:32","guid":{"rendered":"https:\/\/zuviuslifesciences.in\/old\/?p=4708"},"modified":"2020-04-20T07:22:40","modified_gmt":"2020-04-20T07:22:40","slug":"tspyl5-protein-can-help-better-identify-prostate-cancer-progression","status":"publish","type":"post","link":"https:\/\/zuviuslifesciences.in\/old\/tspyl5-protein-can-help-better-identify-prostate-cancer-progression\/","title":{"rendered":"Tspyl5 Protein Can Help Better Identify Prostate Cancer Progression"},"content":{"rendered":"\n<p><strong>Early detection is critical for success in the treatment of prostate cancer. Hence, reliable markers for the malignancy play a vital role in reducing the mortality rate among patients.<\/strong><\/p>\n\n\n\n<h2><strong>Prostate Cancer<\/strong><\/h2>\n\n\n\n<p>Prostate cancer is the most common malignancy reported in adult men. Most patients who develop prostate cancer show no symptoms initially. It is only when the prostate is large enough to affect the urinary system that the malignancy is finally diagnosed. This poses a major challenge in reducing the mortality and morbidity of cancer and hence, finding reliable biomarkers is important in the fight against prostate cancer.<\/p>\n\n\n\n<p>Also read: <a href=\"https:\/\/zuviuslifesciences.in\/old\/prostate-cancer-2\/\" target=\"_blank\" aria-label=\"Prostate Cancer 2 (opens in a new tab)\" rel=\"noreferrer noopener\" class=\"rank-math-link\">Prostate Cancer 2<\/a><\/p>\n\n\n\n<h2><strong>PSA Test<\/strong><\/h2>\n\n\n\n<p>At present, Prostate-specific antigen (PSA), a substance produced by the prostate gland, is used as a marker for prostate cancer. Elevated levels of PSA are used to detect the presence of the malignant cells. However, a high level of PSA does not necessarily indicate the presence of prostate cancer. It could merely be the result of an inflamed or enlarged prostate, both of which are a natural part of the aging process. More reliable tests are needed to help the medical community detect and treat the disease in the increasingly aging population in developed countries.<\/p>\n\n\n\n<h2><strong>New Biomarker<\/strong><\/h2>\n\n\n\n<p>In this context, a recent study by researchers holds special significance.&nbsp;Preliminary studies have identified a specific protein (TSPYL5), which may allow for better identification of prostate cancer progression, and allow for more effective treatment. In addition, the presence of TSPYL5 also seemed to increase the sensitivity of cancer cells to chemotherapy drugs. So measuring the levels of TSPYL5 might be a way to diagnose the patients who have a more aggressive form of the disease.<\/p>\n\n\n\n<p>To quote researcher Senthil Kumar, \u201cTSPYL5 testing could become one of the tools in our fight against prostate cancer. The anticipation is that we can use this biomarker for patients before they undergo any unnecessary and invasive surgeries or drug therapy plans.\u201d Further studies are underway to confirm the validity of these findings<\/p>\n\n\n\n<p>To know more:  <a href=\"https:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/s12885-017-3134-7\" target=\"_blank\" aria-label=\"Testis Specific Y-like 5: Gene Expression, Methylation And Implications For Drug Sensitivity In Prostate Carcinoma (opens in a new tab)\" rel=\"noreferrer noopener\" class=\"rank-math-link\">Testis Specific Y-like 5: Gene Expression, Methylation And Implications For Drug Sensitivity In Prostate Carcinoma<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Early detection is critical for success in the treatment of prostate cancer. Hence, reliable markers for the malignancy play a vital role in reducing the mortality rate among patients. Prostate Cancer Prostate cancer is the most common malignancy reported in adult men. Most patients who develop prostate cancer show no symptoms initially. It is only<\/p>\n","protected":false},"author":1,"featured_media":5052,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":""},"categories":[79],"tags":[103],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/zuviuslifesciences.in\/old\/wp-content\/uploads\/2020\/03\/Prostate-cancer-blog-23-1.jpg?fit=1400%2C863&ssl=1","jetpack-related-posts":[{"id":4915,"url":"https:\/\/zuviuslifesciences.in\/old\/the-statistics-of-prostate-cancer-2\/","url_meta":{"origin":4708,"position":0},"title":"The Statistics Of Prostate Cancer \u2026\u20262","date":"March 17, 2020","format":false,"excerpt":"Worldwide \u00a0statistics show that incidence rate of\u00a0Prostate Cancer\u00a0varies across the \u00a0globe. Men from the developed nations have a much higher occurrence rate than those \u00a0from the developing nations. By the year 2030 the worldwide\u00a0Prostate Cancer\u00a0burden is expected to grow to 1.7 million new cases and 4,99,000 new deaths, \u00a0because of\u2026","rel":"","context":"In &quot;Blog&quot;","img":{"alt_text":"The Statistics Of Prostate Cancer \u2026\u20262","src":"https:\/\/i0.wp.com\/zuviuslifesciences.in\/old\/wp-content\/uploads\/2020\/03\/prostate-cancer-blog-55-1.jpg?fit=500%2C440&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":4709,"url":"https:\/\/zuviuslifesciences.in\/old\/prostate-cancer-2\/","url_meta":{"origin":4708,"position":1},"title":"Prostate Cancer 2","date":"March 14, 2020","format":false,"excerpt":"The Statistics Worldwide statistics show that incidence rate of\u00a0Prostate Cancer\u00a0varies across the globe. Men from the developed nations have a much higher occurrence rate than those from the developing nations. By the year 2030 the worldwide\u00a0Prostate Cancer\u00a0burden is expected to grow to 1.7 million new cases and 4,99,000 new deaths,\u2026","rel":"","context":"In &quot;Blog&quot;","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":6264,"url":"https:\/\/zuviuslifesciences.in\/old\/prostate-cancer-4\/","url_meta":{"origin":4708,"position":2},"title":"Prostate Cancer","date":"April 9, 2020","format":false,"excerpt":"Prostate is a gland found only in males and is a vital part of male reproductive system.Prostate Cancer","rel":"","context":"In &quot;Cancer Type&quot;","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/zuviuslifesciences.in\/old\/wp-content\/uploads\/2020\/04\/image-11-3.jpg?resize=350%2C200&ssl=1","width":350,"height":200},"classes":[]},{"id":4746,"url":"https:\/\/zuviuslifesciences.in\/old\/prostate-cancer\/","url_meta":{"origin":4708,"position":3},"title":"Prostate Cancer","date":"March 14, 2020","format":false,"excerpt":"Signs and Symptoms of Prostate Cancer 1. Generally no symptoms are observed at Early Stage of Prostate Cancer. 2. More advanced Prostate Cancers can sometimes cause symptoms, such as: * Problems passing urine * A slow or weak urinary stream * Need to urinate more often, especially at night *\u2026","rel":"","context":"In &quot;Blog&quot;","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":4689,"url":"https:\/\/zuviuslifesciences.in\/old\/yoga-extra-beneficial-for-prostate-cancer-patients\/","url_meta":{"origin":4708,"position":4},"title":"Yoga: Extra Beneficial For Prostate Cancer Patients","date":"March 14, 2020","format":false,"excerpt":"A great stress buster, yoga has been a part of our lives since time immemorial. Apart from keeping the mind, body, and soul in harmony, yoga has also been known to help as part of the treatment for various illnesses. Practising yoga helps improve blood circulation and enhances lymphatic flow,\u2026","rel":"","context":"In &quot;Blog&quot;","img":{"alt_text":"Yoga: Extra Beneficial For Prostate Cancer Patients","src":"https:\/\/i0.wp.com\/zuviuslifesciences.in\/old\/wp-content\/uploads\/2020\/03\/yoga-blog-19-1.jpg?fit=1200%2C800&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":4704,"url":"https:\/\/zuviuslifesciences.in\/old\/prostate-cancer-3\/","url_meta":{"origin":4708,"position":5},"title":"Prostate Cancer 3","date":"March 14, 2020","format":false,"excerpt":"Modifiable Factors for Prevention A risk factor is anything that affects ones chance of getting a disease, be it diabetes, cardiac problems or cancer. Different cancers have different risk factors. Risk factors are of two kinds: Genetic, related to family history which cannot be changed and Lifestyle related, like eating\u2026","rel":"","context":"In &quot;Blog&quot;","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"_links":{"self":[{"href":"https:\/\/zuviuslifesciences.in\/old\/wp-json\/wp\/v2\/posts\/4708"}],"collection":[{"href":"https:\/\/zuviuslifesciences.in\/old\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zuviuslifesciences.in\/old\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zuviuslifesciences.in\/old\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/zuviuslifesciences.in\/old\/wp-json\/wp\/v2\/comments?post=4708"}],"version-history":[{"count":2,"href":"https:\/\/zuviuslifesciences.in\/old\/wp-json\/wp\/v2\/posts\/4708\/revisions"}],"predecessor-version":[{"id":4715,"href":"https:\/\/zuviuslifesciences.in\/old\/wp-json\/wp\/v2\/posts\/4708\/revisions\/4715"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zuviuslifesciences.in\/old\/wp-json\/wp\/v2\/media\/5052"}],"wp:attachment":[{"href":"https:\/\/zuviuslifesciences.in\/old\/wp-json\/wp\/v2\/media?parent=4708"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zuviuslifesciences.in\/old\/wp-json\/wp\/v2\/categories?post=4708"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zuviuslifesciences.in\/old\/wp-json\/wp\/v2\/tags?post=4708"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}