Vinblastine Sulfate for Injection USP is vincaleukoblastine, sulfate (1:1) (salt). It is the salt of an alkaloid extracted from Vinca rosea Linn., a common fl owering herb known as the periwinkle (more properly known as Catharanthus roseus G. Don). Previously, the generic name was vincaleukoblastine, abbreviated VLB. It is a stathmokinetic oncolytic agent. When treated in vitro with this preparation, growing cells are arrested in metaphase. Chemical and physical evidence indicates that vinblastine sulfate has the molecular formula C46H58O9N4\u2022H2SO4 and that it is a dimeric alkaloid containing both indole and dihydroindole moieties. The structural formula is as follows:<\/p>\n
![\"z-blastin\"](\"https:\/\/i0.wp.com\/www.zuviuslifesciences.in\/media\/120940\/z-blastin-vinblastin.jpg?ssl=1\")
<\/p>\n
Vinblastine sulfate is a white to off-white powder. It is freely soluble in water, soluble in methanol, and slightly soluble in ethanol. It is insoluble in benzene, ether, and naphtha.<\/p>\n
The clinical formulation is supplied in a sterile form for intravenous use only. Vials of Vinblastine Sulfate for Injection USP contain 10 mg (0.011 mmol) of vinblastine sulfate, in the form of a white, amorphous, solid lyophilized plug, without excipients. After reconstitution with sodium chloride solution, the pH of the resulting solution lies in the range of 3.5 to 5.<\/p>\n<\/div>\n<\/div>\n<\/div>\n
[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Composition” tab_id=”1593249431339-a1713a48-c14c”][vc_column_text]Each Vial Contains:<\/p>\n
Vinblastin Sulphate IP equivalent to Vinblastin\u2026\u2026\u2026\u2026..10mg[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Mechanism of Action \/ Pharmcodynamics” tab_id=”1584624217050-ebb8ae5e-43a6″][vc_column_text][\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Pharmacokinetics” tab_id=”1584624459062-96fb7e5b-0e23″][vc_column_text][\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Dosage & Administration” tab_id=”1584625017135-3ffdd9c5-1bd6″][vc_column_text][\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Indications” tab_id=”1584624839401-59481bbb-bdc7″][vc_column_text][\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Warnings” tab_id=”1587924612926-9026122e-aaac”][vc_column_text][\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Precautions” tab_id=”1587924643734-fcc4e0f7-e0eb”][vc_column_text][\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Adverse Reactions (Side Effects)” tab_id=”1587924681199-990fb99f-e39d”][vc_column_text][\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Drug Interactions” tab_id=”1587924714428-204d742f-6852″][vc_column_text][\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Overdose & Contradiction” tab_id=”1587924747096-8ee490ca-c4b1″][vc_column_text][\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Storage” tab_id=”1587924796274-5922ba15-f995″][vc_column_text][\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Presentation” tab_id=”1587924834722-693e27cb-c02b”][vc_column_text][\/vc_column_text][\/vc_tta_section][\/vc_tta_tour][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"
Vinblastine Inj – 10MG<\/h3>\n
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Vincristine sulfate injection has also been shown to be useful in combination with other oncolytic agents in Hodgkin\u2019s disease, non\u2013Hodgkin\u2019s malignant lymphomas, rhabdomyosarcoma, neuroblastoma, and Wilms\u2019 tumor.","rel":"","context":"Similar post","img":{"alt_text":"Z-cristin","src":"https:\/\/i0.wp.com\/zuviuslifesciences.in\/old\/wp-content\/uploads\/2020\/04\/image-44.jpg?fit=615%2C385&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":6740,"url":"https:\/\/zuviuslifesciences.in\/old\/product\/zyrolbine-inj\/","url_meta":{"origin":6701,"position":1},"title":"Zyrolbine Inj","date":"April 27, 2020","format":false,"excerpt":"\u00a0Vinorelbine Inj - 50MG ZYROLBINE is indicated as a single agent or in combination with cisplatin for the first-line treatment of ambulatory patients with unresectable, advanced non-small cell lung cancer (NSCLC). In patients with Stage IV NSCLC, ZYROLBINE is indicated as a single agent or in combination with cisplatin. In\u2026","rel":"","context":"Similar post","img":{"alt_text":"Zyrolbine 50mg_1_1000 x 1000px","src":"https:\/\/i0.wp.com\/zuviuslifesciences.in\/old\/wp-content\/uploads\/2020\/04\/Zyrolbine-50mg_1_1000-x-1000px.jpg?fit=1000%2C1000&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":6753,"url":"https:\/\/zuviuslifesciences.in\/old\/product\/aprepet-z-combi-pack-caps\/","url_meta":{"origin":6701,"position":2},"title":"Aprepet-z Combi Pack Caps","date":"April 27, 2020","format":false,"excerpt":"Aprepitant Combi Pack - 125MG , 80MG Aprepitant, for the treatment of adult patients with chemotherapy-induced nausea and vomiting.","rel":"","context":"Similar post","img":{"alt_text":"Aprepet-Z_1_1000 x 1000px","src":"https:\/\/i0.wp.com\/zuviuslifesciences.in\/old\/wp-content\/uploads\/2020\/04\/Aprepet-Z_1_1000-x-1000px.jpg?fit=1000%2C1000&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":6750,"url":"https:\/\/zuviuslifesciences.in\/old\/product\/zemecon-inj\/","url_meta":{"origin":6701,"position":3},"title":"Zemecon Inj","date":"April 27, 2020","format":false,"excerpt":"Fosaprepitant Inj - 150 MG Fosaprepitant for Injection is a substance P\/neurokinin-1 (NK,) receptor antagonist indicated in adults for use in combination with other antiemetic agents for the: prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy (HEC) including high-dose\u2026","rel":"","context":"Similar post","img":{"alt_text":"Zemecon","src":"https:\/\/i0.wp.com\/zuviuslifesciences.in\/old\/wp-content\/uploads\/2020\/04\/Zemecon-150mg_1_1000-x-1000px.jpg?fit=1000%2C1000&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":6727,"url":"https:\/\/zuviuslifesciences.in\/old\/product\/bleoz-inj\/","url_meta":{"origin":6701,"position":4},"title":"Bleoz Inj","date":"April 27, 2020","format":false,"excerpt":"Bleomycin Inj IP -15 units, 30 units BLEOZ should be considered a palliative treatment. 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